TMEM2 antibody (Middle Region)

Catalog No. ABIN2775385

This Rabbit Polyclonal antibody specifically detects TMEM2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Pig and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for TMEM2 antibody (Middle Region) (ABIN2775385)

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM2 Antibody

Binding Specificity: Middle Region

Sequence: MLTGLCQGCG TRQVVFTSDP HKSYLPVQFQ SPDKAETQRG DPSVISVNGT

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TMEM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1383 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TMEM2 antibody (ABIN2775385)

Zhu, Xie, Li, Huang, Zhao, Hu, Wang, Gu, Gao, Peng: "TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK-STAT signaling pathway." in: Cell death & disease, Vol. 7, Issue 6, pp. e2239, (2016) (PubMed).

Target Details for TMEM2

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Alternative Name: TMEM2

Background: The function of this protein remains unknown.
Alias Symbols: -
Protein Interaction Partner: FBXO6, UBC, ELAVL1,
Protein Size: 1383

Molecular Weight: 154 kDa

Gene ID: 23670

NCBI Accession: NM_013390, NP_037522

UniProt: Q9UHN6