nectin-3 antibody (N-Term)

Catalog No. ABIN2775419

This anti-nectin-3 antibody is a Rabbit Polyclonal antibody detecting nectin-3 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Pig.

Quick Overview for nectin-3 antibody (N-Term) (ABIN2775419)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-nectin-3 Antibody

Binding Specificity: N-Term

Sequence: SGKYICKAVT FPLGNAQSST TVTVLVEPTV SLIKGPDSLI DGGNETVAAI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PVRL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PVRL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 549 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: PVRL3

Background: Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adher
Alias Symbols: CDw113, DKFZP566B0846, FLJ90624, PPR3, PRR3, PVRR3, nectin-3, CD113, CDW113, NECTIN-3
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, KRTAP4-2, RGS20, UBC, BAG3, TIGIT, PVRL2, PVRL1, PARD3, PVR, MLLT4, PVRL3,
Protein Size: 549

Molecular Weight: 61 kDa

Gene ID: 25945

NCBI Accession: NM_015480, NP_056295

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization