AKR1B10 antibody (N-Term)

Catalog No. ABIN2775474

This anti-AKR1B10 antibody is a Rabbit Polyclonal antibody detecting AKR1B10 in WB. Suitable for Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit and Saccharomyces cerevisiae. This Primary Antibody has been cited in 1 publication.

Quick Overview for AKR1B10 antibody (N-Term) (ABIN2775474)

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1B10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKR1B10 Antibody

Binding Specificity: N-Term

Sequence: NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AKR1B10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AKR1B10 antibody (ABIN2775474)

Cheng, Zhang, Kotani, Watanabe, Lee, Wang, Kawashima, Tai, Taniguchi, Honke: "Production of a recombinant single-chain variable-fragment (scFv) antibody against sulfoglycolipid." in: Journal of biochemistry, Vol. 137, Issue 3, pp. 415-21, (2005) (PubMed).

Target Details for AKR1B10

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Alternative Name: AKR1B10

Background: AKR1B10 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
Alias Symbols: AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI, MGC14103
Protein Interaction Partner: NOS2, TERF2IP, ACACA,
Protein Size: 316

Molecular Weight: 35 kDa

Gene ID: 57016

NCBI Accession: NM_020299, NP_064695

UniProt: O60218