RHCE antibody (N-Term)

Catalog No. ABIN2775479

This Rabbit Polyclonal antibody specifically detects RHCE in WB. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for RHCE antibody (N-Term) (ABIN2775479)

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHCE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHCE Antibody

Binding Specificity: N-Term

Purpose: RHCE Antibody - N-terminal region

Sequence: SSKYPRSVRR CLPLCALTLE AALILLFYFF THYDASLEDQ KGLVASYQVG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RHCE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHCE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42567-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-RHCE antibody (ABIN2775479)

McMahon, Okeeffe, , Grayson: "Is hospital-in-the-home (HITH) treatment of bacterial endocarditis safe and effective?" in: Scandinavian journal of infectious diseases, Vol. 40, Issue 1, pp. 40-3, (2007) (PubMed).

Target Details for RHCE

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Alternative Name: RHCE

Background:

Background Information: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease.The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms.

Gene Name: Rh blood group, CcEe antigens

Alternative Symbols: RH, RHC, RHE, Rh4, RHNA, RHPI, RhVI, RH30A, RHIXB, RhVIII, CD240CE, RhIVb(J), RHCe(152N)

Protein Name: Blood group Rh(CE) polypeptide

Molecular Weight: 29kDa

Gene ID: 6006

NCBI Accession: NP_619522

UniProt: P18577