SIGLEC6 antibody (Middle Region)

Catalog No. ABIN2775559

This anti-SIGLEC6 antibody is a Rabbit Polyclonal antibody detecting SIGLEC6 in WB. Suitable for Human, Mouse, Cow, Horse, Dog, Guinea Pig, Rabbit and Rat.

Quick Overview for SIGLEC6 antibody (Middle Region) (ABIN2775559)

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Reactivity: Human, Mouse, Cow, Horse, Dog, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIGLEC6 Antibody

Binding Specificity: Middle Region

Sequence: FSWMSAAPTS LGPRTTQSSV LTITPRPQDH STNLTCQVTF PGAGVTMERT

Predicted Reactivity: Cow: 86%, Dog: 91%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against SIGLEC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 342 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIGLEC6

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Alternative Name: SIGLEC6

Background: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Alias Symbols: CD33L, CD33L1, CDw327, OBBP1, SIGLEC-6, CD327, CD33L2, CDW327
Protein Interaction Partner: TCF4, FHL2, LEP,
Protein Size: 342

Molecular Weight: 36 kDa

Gene ID: 946

NCBI Accession: NM_198846, NP_942143