RGS8 antibody (N-Term)

Catalog No. ABIN2775583

The Rabbit Polyclonal anti-RGS8 antibody has been validated for WB. It is suitable to detect RGS8 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit.

Quick Overview for RGS8 antibody (N-Term) (ABIN2775583)

Target: RGS8 (Regulator of G-Protein Signaling 8 (RGS8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS8 Antibody

Binding Specificity: N-Term

Sequence: NKGMRTRLGC LSHKSDSCSD FTAILPDKPN RALKRLSTEE ATRWADSFDV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RGS8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 198 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS8

Target: RGS8 (Regulator of G-Protein Signaling 8 (RGS8))

Alternative Name: RGS8

Background: RGS8 is a member of the regulator of G protein signaling (RGS) family and is a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.
Alias Symbols: RP11-317P15.2, MGC119067, MGC119068, MGC119069
Protein Interaction Partner: GOLGA2, ADRB2,
Protein Size: 198

Molecular Weight: 22 kDa

Gene ID: 85397

NCBI Accession: NM_033345, NP_203131

UniProt: P57771

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling