Claudin 2 antibody (N-Term)

Catalog No. ABIN2775603

The Rabbit Polyclonal anti-Claudin 2 antibody has been validated for WB. It is suitable to detect Claudin 2 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Sheep.

Quick Overview for Claudin 2 antibody (N-Term) (ABIN2775603)

Target: Claudin 2 (CLDN2)

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 2 Antibody

Binding Specificity: N-Term

Sequence: WMECATHSTG ITQCDIYSTL LGLPADIQAA QAMMVTSSAM SSLACIISVV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CLDN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLDN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: CLDN2

Background: Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[supplied by OMIM].
Alias Symbols: -
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRT31, LNX1, TJP2, PIAS2, UBE2I, KRTAP4-12, WNK4, TJP1,
Protein Size: 230

Molecular Weight: 24 kDa

Gene ID: 9075

NCBI Accession: NM_020384, NP_065117

UniProt: P57739

Pathways: Hepatitis C