RNF2 antibody (Middle Region)

Catalog No. ABIN2775705

This anti-RNF2 antibody is a Rabbit Polyclonal antibody detecting RNF2 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit and Guinea Pig.

Quick Overview for RNF2 antibody (Middle Region) (ABIN2775705)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RNF2 Antibody

Binding Specificity: Middle Region

Sequence: LVFRPHPTLM EKDDSAQTRY IKTSGNATVD HLSKYLAVRL ALEELRSKGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RNF2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 336 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RNF2

Background: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Alias Symbols: BAP1, DING, BAP-1, HIPI3, RING2, RING1B
Protein Interaction Partner: BMI1, SCMH1, HIST2H2AC, UBE2D3, AMBRA1, WASH1, BECN1, ATG14, PIK3C3, TARDBP, SNAI1, NEDD8, UBC, EIF3I, ALYREF, RBM5, RCL1, TRIM28, CEBPZ, SUGP2, G3BP1, AKAP9, YAF2, LRPPRC, KIF20A, RAD50, ARPC4, ABCB6, SMC4, ACOT8, HNRNPDL, THOC1, THRAP3, RBM8A, KIAA0020,
Protein Size: 336

Molecular Weight: 29 kDa

Gene ID: 6045

NCBI Accession: NM_007212, NP_009143

UniProt: Q5TEN1