Retinoic Acid Receptor gamma antibody (Middle Region)
Quick Overview for Retinoic Acid Receptor gamma antibody (Middle Region) (ABIN2775749)
Target
See all Retinoic Acid Receptor gamma (RARG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- QYCRLQKCFE VGMSKEAVRN DRNKKKKEVK EEGSPDSYEL SPQLEELITK
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
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Characteristics
- This is a rabbit polyclonal antibody against RARG. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RARG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 454 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))
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Alternative Name
- RARG
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Background
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RARG is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. RARG controls cell function by directly regulating gene expression.
Alias Symbols: NR1B3, RARC
Protein Interaction Partner: ITGB1BP2, ACY3, RHPN2, ZNF576, LSR, OIP5, IL24, MTMR6, SPHK1, UBC, MRPL12, NKX3-1, HACE1, TNIP1, PNRC2, PNRC1, NCOR2, EIF3I, NCOA1, NR0B2, NCOA3, RXRG, RXRB, RXRA, MAP6, H2AFZ, SUZ12, SRC, AJUBA, SMAD3, HMGA1, NCOR1, NR2F6, SRF, DMPK,
Protein Size: 454 -
Molecular Weight
- 50 kDa
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Gene ID
- 5916
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NCBI Accession
- NM_000966, NP_000957
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UniProt
- P13631
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size
Target
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