BTBD2 antibody (N-Term)

Catalog No. ABIN2775804

This Rabbit Polyclonal antibody specifically detects BTBD2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Zebrafish (Danio rerio).

Quick Overview for BTBD2 antibody (N-Term) (ABIN2775804)

Target: BTBD2 (BTB (POZ) Domain Containing 2 (BTBD2))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BTBD2 Antibody

Binding Specificity: N-Term

Sequence: AFLFNNEVLC DVHFLVGKGL SSQRIPAHRF VLAVGSAVFD AMFNGGMATT

Predicted Reactivity: Cow: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against BTBD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 525 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BTBD2

Target: BTBD2 (BTB (POZ) Domain Containing 2 (BTBD2))

Alternative Name: BTBD2

Background: The C-terminus of BTBD2 binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.
Alias Symbols: -
Protein Interaction Partner: CUL3, TP53, ZNF512B, CDK2, SMAD2, KPNA2, RFWD2, COPS4, COPS3, TOP1, COPS5, COPS6, UBC, DPPA4, UBXN1, CCDC90B, RBM48, BRD7, IGSF21, UBR1, TRIM5, SETDB1, C14orf1, UNC119, CRMP1, GDF9, SMAD1, GBP2, TLE1, TGFBR1, PTN, GAPDH, EEF1A1,
Protein Size: 525

Molecular Weight: 56 kDa

Gene ID: 55643

NCBI Accession: NM_017797, NP_060267

UniProt: Q9BX70