BTBD1 antibody (N-Term)

Catalog No. ABIN2775819

This Rabbit Polyclonal antibody specifically detects BTBD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for BTBD1 antibody (N-Term) (ABIN2775819)

Target: BTBD1 (BTB (POZ) Domain Containing 1 (BTBD1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BTBD1 Antibody

Binding Specificity: N-Term

Sequence: LPLQREPLYN WQATKASLKE RFAFLFNSEL LSDVRFVLGK GRGAAAAGGP

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BTBD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 482 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BTBD1 antibody (ABIN2775819)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for BTBD1

Target: BTBD1 (BTB (POZ) Domain Containing 1 (BTBD1))

Alternative Name: BTBD1

Background: The C-terminus of BTBD1 binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: C15orf1, NS5ATP8
Protein Interaction Partner: CUL3, LRR1, FMOD, NEDD8, COPS4, COPS5, COPS3, UBC, TOP1, COPS6, CUL5, SUMO1, TRIM5,
Protein Size: 482

Molecular Weight: 53 kDa

Gene ID: 53339

NCBI Accession: NM_025238, NP_079514

UniProt: Q9H0C5