TRIM50 antibody (Middle Region)

Catalog No. ABIN2775829

Product Details anti-TRIM50 Antibody

Target: TRIM50 (Tripartite Motif Containing 50 (TRIM50))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM50 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DWRLGVIKGT ASRKGKLNRS PEHGVWLIGL KEGRVYEAFA CPRVPLPVAG

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRIM50. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM50

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 487 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM50

Target: TRIM50 (Tripartite Motif Containing 50 (TRIM50))

Alternative Name: TRIM50 (TRIM50 Products)

Background: TRIM50 belongs to the TRIM/RBCC family. It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM50 is an E3 ubiquitin-protein ligase.
Alias Symbols: FLJ32804, MGC138357, MGC138359, TRIM50A
Protein Interaction Partner: TNK2, HDAC6, SQSTM1, UBC, UBE2D4, UBE2E3, UBE2N, UBE2E2, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 487

Molecular Weight: 55 kDa

Gene ID: 135892

NCBI Accession: NM_178125, NP_835226

UniProt: Q86XT4