PAX5 antibody (N-Term)

Catalog No. ABIN2775953

This Rabbit Polyclonal antibody specifically detects PAX5 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for PAX5 antibody (N-Term) (ABIN2775953)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PAX5 Antibody

Binding Specificity: N-Term

Sequence: CVSKILGRYY ETGSIKPGVI GGSKPKVATP KVVEKIAEYK RQNPTMFAWE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PAX5. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 391 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background: The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Alias Symbols: BSAP
Protein Interaction Partner: TBP, RB1, EP300, RUNX1, TLE4, DAXX, KPNA1, KPNA2, ID2, ID3, CREBBP, MYB, PAX5, ETS1, EBF1,
Protein Size: 391

Molecular Weight: 42 kDa

Gene ID: 5079

NCBI Accession: NM_016734, NP_057953

UniProt: Q02548