TRIM14 antibody (Middle Region)

Catalog No. ABIN2775984

This Rabbit Polyclonal antibody specifically detects TRIM14 in WB. It exhibits reactivity toward Human, Mouse, Horse and Ratand has been mentioned in 1 publication.

Quick Overview for TRIM14 antibody (Middle Region) (ABIN2775984)

Target: TRIM14 (Tripartite Motif Containing 14 (TRIM14))

Reactivity: Human, Mouse, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM14 Antibody

Binding Specificity: Middle Region

Sequence: LVEAVESTLQ TPLDIRLKES INCQLSDPSS TKPGTLLKTS PSPERSLLLK

Predicted Reactivity: Horse: 92%, Human: 100%, Mouse: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TRIM14. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRIM14 antibody (ABIN2775984)

Zhou, Jia, Xue, Dou, Ma, Zhao, Jiang, He, Jin, Wang: "TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 2, pp. E245-54, (2014) (PubMed).

Target Details for TRIM14

Target: TRIM14 (Tripartite Motif Containing 14 (TRIM14))

Alternative Name: TRIM14

Background: The protein encoded byTRIM14 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Four alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Four alternatively spliced transcript variants for this gene have been described.
Alias Symbols: KIAA0129
Protein Interaction Partner: RNF2, UBC,
Protein Size: 442

Molecular Weight: 50 kDa

Gene ID: 9830

NCBI Accession: NM_014788, NP_055603

UniProt: Q14142