CNBP antibody (N-Term)

Catalog No. ABIN2776037

The Rabbit Polyclonal anti-CNBP antibody (ABIN2776037) specifically detects CNBP in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig and Rabbit samples.

Quick Overview for CNBP antibody (N-Term) (ABIN2776037)

Target: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNBP Antibody

Binding Specificity: N-Term

Sequence: SSNECFKCGR SGHWARECPT GGGRGRGMRS RGRGGFTSDR GFQFVSSSLP

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CNBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 177 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNBP

Target: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Alternative Name: CNBP

Background: CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Protein Interaction Partner: UBC, EZH2, BMI1, SUZ12, RNF2, BZW2, FERMT2, PFAS, EIF6, HSPA9, DFFA, MAPK14, PAN2, VCAM1, ITGA4, KCND3, Mis12, Cnbp, ZWINT, MYH4, FKTN, PCBP2, RPL31, HNRNPA3, BRIX1, APOBEC3C, RBMX, RSL1D1, RPL36, HNRNPUL1, EBNA1BP2, IGF2BP3, IGF2BP1, SYNCRIP, HNRNPR, DAP
Protein Size: 177

Molecular Weight: 19 kDa

Gene ID: 7555

NCBI Accession: NM_003418, NP_003409

UniProt: P62633