GABRA1 antibody (N-Term)

Catalog No. ABIN2776106

The Rabbit Polyclonal anti-GABRA1 antibody has been validated for WB. It is suitable to detect GABRA1 in samples from Rat, Human, Mouse, Cow, Dog, Rabbit and Pig.

Quick Overview for GABRA1 antibody (N-Term) (ABIN2776106)

Target: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Reactivity: Rat, Human, Mouse, Cow, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRA1 Antibody

Binding Specificity: N-Term

Sequence: WAWILLLSTL TGRSYGQPSL QDELKDNTTV FTRILDRLLD GYDNRLRPGL

Predicted Reactivity: Cow: 100%, Dog: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against GABRA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 456 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRA1

Target: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Alternative Name: GABRA1

Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Alias Symbols: EJM, ECA4, EJM5
Protein Interaction Partner: UBQLN1, PRKCG, PRKCD, PPP3CA,
Protein Size: 456

Molecular Weight: 52 kDa

Gene ID: 2554

NCBI Accession: NM_000806, NP_000797

UniProt: P14867