Serotonin Receptor 3B antibody (N-Term)

Catalog No. ABIN2776184

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 3B in WB, IHC and IF. It exhibits reactivity toward Human, Rat, Mouse, Cow, Guinea Pig, Pig, Dog and Rabbit.

Quick Overview for Serotonin Receptor 3B antibody (N-Term) (ABIN2776184)

Target: Serotonin Receptor 3B (HTR3B)

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Serotonin Receptor 3B Antibody

Binding Specificity: N-Term

Sequence: PLWACILVAA GILATDTHHP QDSALYHLSK QLLQKYHKEV RPVYNWTKAT

Predicted Reactivity: Cow: 79%, Dog: 77%, Guinea Pig: 79%, Human: 100%, Mouse: 77%, Pig: 86%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against HTR3B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 441 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Serotonin Receptor 3B

Target: Serotonin Receptor 3B (HTR3B)

Alternative Name: HTR3B

Background: The product of HTR3B belongs to the ligand-gated ion channel receptor superfamily. HTR3B encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation.
Alias Symbols: 5-HT3B
Protein Size: 441

Molecular Weight: 49 kDa

Gene ID: 9177

NCBI Accession: NM_006028, NP_006019

UniProt: O95264

Pathways: Synaptic Membrane