KCNIP2 antibody (N-Term)

Catalog No. ABIN2776207

The Rabbit Polyclonal anti-KCNIP2 antibody (ABIN2776207) specifically detects KCNIP2 in WB. The antibody is reactive with Human, Dog and Rabbit samples.

Quick Overview for KCNIP2 antibody (N-Term) (ABIN2776207)

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Reactivity: Human, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNIP2 Antibody

Binding Specificity: N-Term

Sequence: LKQRFLKLLP CCGPQALPSV SEIGRVFRFL GDSSLPSALA APASLRPHRP

Predicted Reactivity: Dog: 86%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against KCNIP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 285 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNIP2

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Alternative Name: KCNIP2

Background: KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Alias Symbols: DKFZp566L1246, KCHIP2, MGC17241
Protein Interaction Partner: KCND2, KCNIP1, KCNIP2, KCNE4, KCND3, KCNIP4,
Protein Size: 285

Molecular Weight: 32 kDa

Gene ID: 30819

NCBI Accession: NM_014591, NP_055406