CHRFAM7A antibody (N-Term)

Catalog No. ABIN2776280

Cited in 1 publication. The Rabbit Polyclonal anti-CHRFAM7A antibody (ABIN2776280) specifically detects CHRFAM7A in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Cow, Horse and Rabbit samples.

Quick Overview for CHRFAM7A antibody (N-Term) (ABIN2776280)

Target: CHRFAM7A (CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10) and FAM7A (Family with Sequence Similarity 7A, Exons A-E) Fusion (CHRFAM7A))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRFAM7A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRFAM7A Antibody

Binding Specificity: N-Term

Sequence: QFQLLIQHLW IAANCDIADE RFDATFHTNV LVNSSGHCQY LPPGIFKSSC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CHRFAM7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRFAM7A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CHRFAM7A antibody (ABIN2776280)

Trombino, Cesario, Margaritora, Granone, Motta, Falugi, Russo: "Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway." in: Cancer research, Vol. 64, Issue 1, pp. 135-45, (2004) (PubMed).

Target Details for CHRFAM7A

Target: CHRFAM7A (CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10) and FAM7A (Family with Sequence Similarity 7A, Exons A-E) Fusion (CHRFAM7A))

Alternative Name: CHRFAM7A

Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7 is located on chromosome 15 in a region associated with several neuropsychiatric disorders. CHRFAM7A is is a hybrid between CHRNA7 and FAM7A.
Alias Symbols: D-10, CHRNA7, CHRNA7-DR1
Protein Size: 412

Molecular Weight: 45 kDa

Gene ID: 89832

NCBI Accession: NM_139320, NP_647536

UniProt: Q494W8