NCOA4 antibody (C-Term)

Catalog No. ABIN2776441

This anti-NCOA4 antibody is a Rabbit Polyclonal antibody detecting NCOA4 in WB. Suitable for Human, Rat, Cow, Dog, Horse and Pig.

Quick Overview for NCOA4 antibody (C-Term) (ABIN2776441)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivity: Human, Rat, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCOA4 Antibody

Binding Specificity: C-Term

Sequence: KEVPGTEDRA GKQKFKSPMN TSWCSFNTAD WVLPGKKMGN LSQLSSGEDK

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NCOA4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 614 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: NCOA4

Background: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.
Alias Symbols: ARA70, DKFZp762E1112, ELE1, PTC3, RFG
Protein Interaction Partner: UBC, AR, RXRA, ATXN2, AKT1, VDR, GTF2B, KAT2B, RNF14, PPARG, NR3C1, ESR1,
Protein Size: 614

Molecular Weight: 70 kDa

Gene ID: 8031

NCBI Accession: NM_005437, NP_005428

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway