HOXC9 antibody (Middle Region)
Quick Overview for HOXC9 antibody (Middle Region) (ABIN2776470)
Target
See all HOXC9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- DRAPQTLPSP EADALAGSKH KEEKADLDPS NPVANWIHAR STRKKRCPYT
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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Characteristics
- This is a rabbit polyclonal antibody against HOXC9. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HOXC9
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 260 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1." in: Neuro-oncology, Vol. 18, Issue 6, pp. 819-29, (2016) (PubMed).
: "Analysis of HOX gene expression patterns in human breast cancer." in: Molecular biotechnology, Vol. 56, Issue 1, pp. 64-71, (2014) (PubMed).
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: "Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1." in: Neuro-oncology, Vol. 18, Issue 6, pp. 819-29, (2016) (PubMed).
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- HOXC9 (Homeobox C9 (HOXC9))
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Alternative Name
- HOXC9
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Background
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HOXC9 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.
Alias Symbols: HOX3, HOX3B
Protein Interaction Partner: LPXN, ZNF384, CBX6, GTF2A1L, IRF9, NMI, PCGF2, ZFP36, POU2F1, POLR2D, HOXD9, HOXD1, HOXC13, ELAVL2, POLR3D, GMNN,
Protein Size: 260 -
Molecular Weight
- 29 kDa
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Gene ID
- 3225
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NCBI Accession
- NM_006897, NP_008828
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UniProt
- P31274
Target
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