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VSX1 antibody (Middle Region)

The Rabbit Polyclonal anti-VSX1 antibody has been validated for WB. It is suitable to detect VSX1 in samples from Human, Mouse, Cow, Dog, Horse, Pig and Saccharomyces cerevisiae.
Catalog No. ABIN2776514

Quick Overview for VSX1 antibody (Middle Region) (ABIN2776514)

Target

See all VSX1 Antibodies
VSX1 (Visual System Homeobox 1 (VSX1))

Reactivity

Human, Mouse, Cow, Dog, Horse, Pig, Saccharomyces cerevisiae

Host

  • 27
Rabbit

Clonality

  • 27
Polyclonal

Conjugate

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VSX1 antibody is un-conjugated

Application

  • 20
  • 10
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequence

    FLPPRGPEPA APLAPSRPPP ALGRQKRSDS VSTSDEDSQS EDRNDLKASP

    Predicted Reactivity

    Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Yeast: 86%

    Characteristics

    This is a rabbit polyclonal antibody against VSX1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human VSX1
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 365 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    VSX1 (Visual System Homeobox 1 (VSX1))

    Alternative Name

    VSX1

    Background

    VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: KTCN, PPCD, PPD, RINX, KTCN1, CAASDS
    Protein Size: 365

    Molecular Weight

    38 kDa

    Gene ID

    30813

    NCBI Accession

    NM_014588, NP_055403

    UniProt

    Q9NZR4
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