TRIP4 antibody (Middle Region)

Catalog No. ABIN2776529

The Rabbit Polyclonal anti-TRIP4 antibody has been validated for WB. It is suitable to detect TRIP4 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for TRIP4 antibody (Middle Region) (ABIN2776529)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIP4 Antibody

Binding Specificity: Middle Region

Sequence: VCEQEGSGPC LFCGTLVCTH EEQDILQRDS NKSQKLLKKL MSGVENSGKV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against TRIP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 581 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Alternative Name: TRIP4

Background: TRIP4 is a transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. TRIP4 plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. TRIP4 acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. It plays a role in androgen receptor transactivation and in testicular function
Alias Symbols: ASC1, ASC-1, HsT17391
Protein Interaction Partner: FUS, NEK6, RELA, UBC, MED11, MED8, MED10, MED25, MED28, MED15, MED4, RCOR1, MED13, MED12, MED24, MED27, MED17, MED23, MED1, POLR2A, PPARG, ESR2, XBP1, NR2F2, PAX9, ASCC2, ASCC3, THRB, RARA, TRIP4, EP300, NCOA1, GTF2A1, CREBBP, TBP, AR, RXRA, JUN, NFKB1, E
Protein Size: 581

Molecular Weight: 66 kDa

Gene ID: 9325

NCBI Accession: NM_016213, NP_057297

UniProt: Q15650