SECISBP2 antibody (N-Term)

Catalog No. ABIN2776565

This Rabbit Polyclonal antibody specifically detects SECISBP2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for SECISBP2 antibody (N-Term) (ABIN2776565)

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SECISBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SECISBP2 Antibody

Binding Specificity: N-Term

Sequence: FDSERADGTI SSEIKSARGS HHLSIYAENS LKSDGYHKRT DRKSRIIAKN

Predicted Reactivity: Cow: 76%, Dog: 86%, Guinea Pig: 91%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SECISBP2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 854 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Alternative Name: SECISBP2

Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
Alias Symbols: DKFZp686C09169, SBP2
Protein Interaction Partner: GOLGA2, SMAD9, APP, ATXN7L3,
Protein Size: 854

Molecular Weight: 95 kDa

Gene ID: 79048

NCBI Accession: NM_024077, NP_076982

UniProt: Q96T21