SRSF12 antibody (Middle Region)
Quick Overview for SRSF12 antibody (Middle Region) (ABIN2776616)
Target
See all SRSF12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- RSRSKSLQKR SKSIGKSQSS SPQKQTSSGT KSRSHGRHSD SIARSPCKSP
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against SRrp35. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SRrp35
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 261 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).
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: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).
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- SRSF12 (serine/arginine-Rich Splicing Factor 12 (SRSF12))
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Alternative Name
- SRrp35
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Background
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SRrp35 is a splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation.
Alias Symbols: FLJ14459, FLJ33484, FLJ41221, RP11-63L7.3, SFRS19, SRrp35, SFRS13B
Protein Interaction Partner: SRPK2, SRPK1, CDK6, MAGOH,
Protein Size: 261 -
Molecular Weight
- 30 kDa
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Gene ID
- 135295
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NCBI Accession
- NM_080743, NP_542781
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UniProt
- Q8WXF0
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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