Nanos Homolog 1 antibody (Middle Region)

Catalog No. ABIN2776686

The Rabbit Polyclonal anti-Nanos Homolog 1 antibody has been validated for WB. It is suitable to detect Nanos Homolog 1 in samples from Human, Mouse, Rat, Pig and Rabbit.

Quick Overview for Nanos Homolog 1 antibody (Middle Region) (ABIN2776686)

Target: Nanos Homolog 1 (NANOS1)

Reactivity: Human, Mouse, Rat, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nanos Homolog 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nanos Homolog 1 Antibody

Binding Specificity: Middle Region

Sequence: DDDDDSDEPG SRGRYLGSAL ELRALELCAG PAEAGLLEER FAELSPFAGR

Predicted Reactivity: Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NANOS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NANOS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 292 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nanos Homolog 1

Target: Nanos Homolog 1 (NANOS1)

Alternative Name: NANOS1

Background: NANOS1 contains 1 nanos-type zinc finger and belongs to the nanos family. It may regulate translation of specific mRNAs by forming a complex with PUM2 that associates with the 3' untranslated regions (UTRs) of mRNA targets.
Alias Symbols: NOS1
Protein Interaction Partner: PUM2, GRIN1, GRIN2D,
Protein Size: 292

Molecular Weight: 30 kDa

Gene ID: 340719

NCBI Accession: NM_199461, NP_955631

UniProt: Q8WY41

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction