MBNL1 antibody (Middle Region)

Catalog No. ABIN2776697

The Rabbit Polyclonal anti-MBNL1 antibody has been validated for WB and IHC. It is suitable to detect MBNL1 in samples from Human, Rat, Mouse, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for MBNL1 antibody (Middle Region) (ABIN2776697)

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MBNL1 Antibody

Binding Specificity: Middle Region

Sequence: AMTQSAVKSL KRPLEATFDL GIPQAVLPPL PKRPALEKTN GATAVFNTGI

Predicted Reactivity: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MBNL1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBNL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 343 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MBNL1 antibody (ABIN2776697)

Coram, Stillwagon, Guggilam, Jenkins, Swanson, Ladd: "Muscleblind-like 1 is required for normal heart valve development in vivo." in: BMC developmental biology, Vol. 15, pp. 36, (2015) (PubMed).

Target Details for MBNL1

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Alternative Name: MBNL1

Background: MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.
Alias Symbols: EXP, MBNL, EXP35, EXP40, EXP42
Protein Interaction Partner: DAB1, AES, AEN, UBC, ABI3BP, ZNHIT3, VCAM1, ITGA4, IDH3A, FN1, TIAL1, APP, BIN1, ITSN2, DDX17, HNRNPL, HNRNPK, HNRNPH3, HNRNPH2, HNRNPH1, HNRNPF, HNRNPA2B1, DHX9, DDX5,
Protein Size: 343

Molecular Weight: 38 kDa

Gene ID: 4154

NCBI Accession: NM_021038

UniProt: Q86VM6

Pathways: Ribonucleoprotein Complex Subunit Organization