MBNL1 antibody (C-Term)

Catalog No. ABIN2776698

Cited in 1 publication. The Rabbit Polyclonal anti-MBNL1 antibody (ABIN2776698) specifically detects MBNL1 in WB and IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for MBNL1 antibody (C-Term) (ABIN2776698)

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MBNL1 Antibody

Binding Specificity: C-Term

Purpose: MBNL1 Antibody - C-terminal region

Sequence: LCPQQQHLPQ VFPSLQQPQP TSPILDASTL LGATSCPAAA AGKMIPIISA

Predicted Reactivity: Human: 100%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MBNL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MBNL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105859

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MBNL1 antibody (ABIN2776698)

Adam-Vizi: "Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources." in: Antioxidants & redox signaling, Vol. 7, Issue 9-10, pp. 1140-9, (2005) (PubMed).

Target Details for MBNL1

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Alternative Name: MBNL1

Background:

Background Information: MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.

Gene Name: Muscleblind-like splicing regulator 1

Alternative Symbols: EXP, MBNL

Protein Name: Muscleblind-like protein EXP40s EMBL AAP30726.1

Molecular Weight: 37kDa

Gene ID: 4154

NCBI Accession: NP_997179

UniProt: Q86UV9

Pathways: Ribonucleoprotein Complex Subunit Organization