FZD5 antibody (Middle Region)

Catalog No. ABIN2776705

The Rabbit Polyclonal anti-FZD5 antibody is suitable to detect FZD5 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for FZD5 antibody (Middle Region) (ABIN2776705)

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FZD5 Antibody

Binding Specificity: Middle Region

Sequence: CYLYEQHYRE SWEAALTCAC PGHDTGQPRA KPEYWVLMLK YFMCLVVGIT

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against FZD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FZD5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 585 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FZD5

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Alternative Name: FZD5

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
Alias Symbols: C2orf31, DKFZP434E2135, HFZ5, MGC129692
Protein Interaction Partner: LRP6, UBTD1, LZTFL1, ABI3BP, RGS2, RPS6KA6, GSK3B, UBC, Ror2, GOPC, WNT7A, WNT5A,
Protein Size: 585

Molecular Weight: 62 kDa

Gene ID: 7855

NCBI Accession: NM_003468, NP_003459

UniProt: Q13467

Pathways: WNT Signaling