WDR12 antibody (C-Term)

Catalog No. ABIN2776745

The Rabbit Polyclonal anti-WDR12 antibody has been validated for WB and IHC. It is suitable to detect WDR12 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio).

Quick Overview for WDR12 antibody (C-Term) (ABIN2776745)

Target: WDR12 (WD Repeat Domain 12 (WDR12))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-WDR12 Antibody

Binding Specificity: C-Term

Sequence: DTRSCKAPLY DLAAHEDKVL SVDWTDTGLL LSGGADNKLY SYRYSPTTSH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 89%

Characteristics: This is a rabbit polyclonal antibody against WDR12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 423 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDR12

Target: WDR12 (WD Repeat Domain 12 (WDR12))

Alternative Name: WDR12

Background: WDR12 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The function of this protein is not known.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The function of this protein is not known.
Alias Symbols: YTM1
Protein Interaction Partner: UBC, RNF2, BMI1, WDR92, VPS25, ACBD3, VPS29, VPS36, RPUSD2, SNF8, TOM1, TSN, TBCD, SRSF5, PPP3CB, PPP2CB, WDR12, PES1, BOP1, VPS37B, UBE2Z, TBC1D13, SEPHS1, TOMM34, SUGT1, VAT1, USP14, XPO1, TSG101, INPP1, DDX6, GRK5, SIRT7, SUMO2, HIST1H1C, WDR5, NOTCH1,
Protein Size: 423

Molecular Weight: 47 kDa

Gene ID: 55759

NCBI Accession: NM_018256, NP_060726

UniProt: Q9GZL7