ASS1 antibody (C-Term)

Catalog No. ABIN2776769

This anti-ASS1 antibody is a Rabbit Polyclonal antibody detecting ASS1 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Goat and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for ASS1 antibody (C-Term) (ABIN2776769)

Target: ASS1 (Argininosuccinate Synthase 1 (ASS1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ASS1 Antibody

Binding Specificity: C-Term

Sequence: SVLKGQVYIL GRESPLSLYN EELVSMNVQG DYEPTDATGF ININSLRLKE

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ASS. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ASS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ASS1 antibody (ABIN2776769)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Target Details for ASS1

Target: ASS1 (Argininosuccinate Synthase 1 (ASS1))

Background: ASS catalyzes the penultimate step of the arginine biosynthetic pathway.The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ASS1, CTLN1, DKFZp434P0216, ASS
Protein Interaction Partner: ASS1, UBC, ASB18, ASB9, NHLRC2, ATG3, CNDP2, NANS, TNFAIP8, NAMPT, DPP3, RPL23, CTSA, PEPD, MVD, HSPA9, GSS, GBP2, EIF4E, DLD, CAPN1, FBXO6, LATS1, MT2A, MLH1, JAK2, PTPN1, GIT2, SPR, APP, USP4, TERF2, TERF1, SUMO2, AI837181, MYC, ASCC2, AKTIP, ARAF, ELN,
Protein Size: 412

Molecular Weight: 45 kDa

Gene ID: 445

NCBI Accession: NM_054012, NP_446464

UniProt: P00966

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin