PLA2G5 antibody (Middle Region)

Catalog No. ABIN2776806

The Rabbit Polyclonal anti-PLA2G5 antibody has been validated for WB. It is suitable to detect PLA2G5 in samples from Rat, Human, Cow, Dog, Horse and Guinea Pig. There is 1 publication available.

Quick Overview for PLA2G5 antibody (Middle Region) (ABIN2776806)

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Reactivity: Rat, Human, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G5 Antibody

Binding Specificity: Middle Region

Sequence: YRFAWGVVTC EPGPFCHVNL CACDRKLVYC LKRNLRSYNP QYQYFPNILC

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PLA2G5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLA2G5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 138 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PLA2G5 antibody (ABIN2776806)

Yamaguchi, Zacharia, Laidlaw, Balestrieri: "PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 131-41, (2016) (PubMed).

Target Details for PLA2G5

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Alternative Name: PLA2G5

Background: This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholip
Alias Symbols: DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2), FRFB
Protein Interaction Partner: PLA2G4A,
Protein Size: 138

Molecular Weight: 14 kDa

Gene ID: 5322

NCBI Accession: NM_000929, NP_000920

UniProt: P39877

Pathways: Inositol Metabolic Process