SLC13A3 antibody (N-Term)

Catalog No. ABIN2776814

The Rabbit Polyclonal anti-SLC13A3 antibody has been validated for WB. It is suitable to detect SLC13A3 in samples from Human, Dog, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for SLC13A3 antibody (N-Term) (ABIN2776814)

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Reactivity: Human, Dog, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC13A3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC13A3 Antibody

Binding Specificity: N-Term

Sequence: MAVYWCTEAL PLSVTALLPI VLFPFMGILP SNKVCPQYFL DTNFLFLSGL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SLC13A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC13A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 602 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC13A3

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Alternative Name: SLC13A3

Background: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
Alias Symbols: NADC3, SDCT2
Protein Size: 602

Molecular Weight: 66 kDa

Gene ID: 64849

NCBI Accession: NM_022829, NP_073740

UniProt: Q8WWT9

Pathways: Dicarboxylic Acid Transport