CEACAM6 antibody (Middle Region)

Catalog No. ABIN2776853

There is 1 publication for this product available. The Rabbit Polyclonal anti-CEACAM6 antibody is suitable to detect CEACAM6 in samples from Human. It has been validated for WB and IHC.

Quick Overview for CEACAM6 antibody (Middle Region) (ABIN2776853)

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CEACAM6 Antibody

Binding Specificity: Middle Region

Sequence: EIQNPASANR SDPVTLNVLY GPDGPTISPS KANYRPGENL NLSCHAASNP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CEACAM6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CEACAM6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 344 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CEACAM6 antibody (ABIN2776853)

Kobayashi, Miki, Ebina, Abe, Mori, Narumi, Suzuki, Sato, Maemondo, Endo, Inoue, Kumamoto, Kondo, Yamada-Okabe, Nukiwa, Sasano: "Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma." in: British journal of cancer, Vol. 107, Issue 10, pp. 1745-53, (2012) (PubMed).

Target Details for CEACAM6

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Alternative Name: CEACAM6

Background: Many breast, pancreatic, colonic and non-small-cell lung carcinoma lines express CEACAM6 and CEACAM5, and antibodies to both can affect tumor cell growth in vitro and in vivo. CEACAM6 expression is elevated in many solid tumors, but variable as a function of histotype. It may be a promising target for antibody-based therapy.
Alias Symbols: CD66c, CEAL, NCA
Protein Interaction Partner: CARTPT, CEACAM6, CEACAM8, CEACAM7, CEACAM5, CEACAM1, APP,
Protein Size: 344

Molecular Weight: 38 kDa

Gene ID: 4680

NCBI Accession: NM_002483, NP_002474

UniProt: P40199