HMGCS2 antibody (C-Term)

Catalog No. ABIN2776881

This anti-HMGCS2 antibody is a Rabbit Polyclonal antibody detecting HMGCS2 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Goat, Horse and Cow.

Quick Overview for HMGCS2 antibody (C-Term) (ABIN2776881)

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Goat, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGCS2 Antibody

Binding Specificity: C-Term

Sequence: DLPKRLASRK CVSPEEFTEI MNQREQFYHK VNFSPPGDTN SLFPGTWYLE

Predicted Reactivity: Cow: 79%, Dog: 100%, Goat: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGCS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HMGCS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 508 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGCS2

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Alternative Name: HMGCS2

Background: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Alias Symbols: -
Protein Interaction Partner: UBC, APP, YWHAQ,
Protein Size: 508

Molecular Weight: 56 kDa

Gene ID: 3158

NCBI Accession: NM_005518, NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha