CHST7 antibody (Middle Region)

Catalog No. ABIN2776908

The Rabbit Polyclonal anti-CHST7 antibody has been validated for WB. It is suitable to detect CHST7 in samples from Mouse, Human, Dog, Cow, Guinea Pig, Rabbit and Rat. There is 1 publication available.

Quick Overview for CHST7 antibody (Middle Region) (ABIN2776908)

Target: CHST7 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 7 (CHST7))

Reactivity: Mouse, Human, Dog, Cow, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHST7 Antibody

Binding Specificity: Middle Region

Sequence: DLGVLVPLLR DPGLNLKVVQ LFRDPRAVHN SRLKSRQGLL RESIQVLRTR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CHST7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHST7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 486 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CHST7 antibody (ABIN2776908)

Thiselton, McDowall, Brandau, Ramser, dEsposito, Bhattacharya, Ross, Hardcastle, Meindl: "An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders." in: Genomics, Vol. 79, Issue 4, pp. 560-72, (2002) (PubMed).

Target Details for CHST7

Target: CHST7 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 7 (CHST7))

Alternative Name: CHST7

Background: CHST7 belongs to the sulfotransferase family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This protein mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of the family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes.This gene belongs to the sulfotransferase gene family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes. This gene is part of a gene cluster on chromosome Xp11.23.
Alias Symbols: C6ST-2
Protein Interaction Partner: UBC,
Protein Size: 486

Molecular Weight: 53 kDa

Gene ID: 56548

NCBI Accession: NM_019886, NP_063939

UniProt: Q9NS84

Pathways: Glycosaminoglycan Metabolic Process