Laminin beta 3 antibody (Middle Region)

Catalog No. ABIN2776940

Product Details anti-Laminin beta 3 Antibody

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Guinea Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ERIKQKYAEL KDRLGQSSML GEQGARIQSV KTEAEELFGE TMEMMDRMKD

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against LAMB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LAMB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1172 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Laminin beta 3

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Alternative Name: LAMB3 (LAMB3 Products)

Background: The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bul
Alias Symbols: LAMNB1, LAM5, BM600-125KDA
Protein Interaction Partner: UBC, PDIA3, LAMA3, THBS1, LAMC2, COL7A1, BMP1,
Protein Size: 1172

Molecular Weight: 128 kDa

Gene ID: 3914

NCBI Accession: NM_000228, NP_000219

UniProt: Q13751

Pathways: Brown Fat Cell Differentiation