Cytokeratin 19 antibody (Middle Region)

Catalog No. ABIN2776961

This Rabbit Polyclonal antibody specifically detects Cytokeratin 19 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Pig, Cow, Horse, Guinea Pig, Sheep and Goat.

Quick Overview for Cytokeratin 19 antibody (Middle Region) (ABIN2776961)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Pig, Cow, Horse, Guinea Pig, Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytokeratin 19 Antibody

Binding Specificity: Middle Region

Sequence: DMRSQYEVMA EQNRKDAEAW FTSRTEELNR EVAGHTEQLQ MSRSEVTDLR

Predicted Reactivity: Cow: 86%, Dog: 100%, Goat: 77%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 77%

Characteristics: This is a rabbit polyclonal antibody against KRT19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KRT19

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Alternative Name: KRT19

Background: KRT19 involved in the organization of myofibers. Together with KRT8, KRT19 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Alias Symbols: CK19, K19, K1CS
Protein Interaction Partner: CEP57L1, PPP1R18, HAUS1, IKZF3, POLR1C, EIF4E2, UBE2I, KRT19, KRT2, KIFC3, FAM124B, CARD9, CCDC146, EIF4ENIF1, C1orf109, AMOTL2, TBC1D7, TFPT, UBC, MDM2, EED, KDM1A, BAG3, PAN2, VCAM1, ITGA4, FN1, EIF4A3, MAGOH, GRB2, CRK, SUMO1, SUMO2, SUMO3, UCHL5, POU5
Protein Size: 400

Molecular Weight: 44 kDa

Gene ID: 3880

NCBI Accession: NM_002276, NP_002267

UniProt: P08727