KRT17 antibody (C-Term)

Catalog No. ABIN2776962

This Rabbit Polyclonal antibody specifically detects KRT17 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig, Dog, Rabbit, Sheep, Horse and Zebrafish (Danio rerio).

Quick Overview for KRT17 antibody (C-Term) (ABIN2776962)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog, Rabbit, Sheep, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KRT17 Antibody

Binding Specificity: C-Term

Sequence: IATYRRLLEG EDAHLTQYKK EPVTTRQVRT IVEEVQDGKV ISSREQVHQT

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against KRT17. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: KRT17

Background: KRT17 is type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in its gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.KRT17 encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Alias Symbols: K17, PC, PC2, PCHC1
Protein Interaction Partner: TRIM69, UBC, MDM2, IGF2BP3, IKBKG, PA2G4, CRYZ, KDM1A, GRB2, Iqcb1, Nphp1, Invs, CALR, ILF3, UBASH3B, SHC1, PIK3R2, INPPL1, EPS15, CRK, AP2M1, CBL, COPS5, SUMO2, YWHAQ, APC, USP1, UCHL1, CCDC85B, KRT7, KRT6A, EGFR, KRT72, KRT8,
Protein Size: 432

Molecular Weight: 48 kDa

Gene ID: 3872

NCBI Accession: NM_000422, NP_000413

UniProt: Q04695