GHRHR antibody (Middle Region)

Catalog No. ABIN2777009

This Rabbit Polyclonal antibody specifically detects GHRHR in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig, Cow, Sheep, Dog, Rabbit and Horse.

Quick Overview for GHRHR antibody (Middle Region) (ABIN2777009)

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Reactivity: Human, Rat, Mouse, Pig, Cow, Sheep, Dog, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHRHR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GHRHR Antibody

Binding Specificity: Middle Region

Sequence: PYPVACPVPL ELLAEEESYF STVKIIYTVG HSISIVALFV AITILVALRR

Predicted Reactivity: Cow: 77%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 77%, Rabbit: 93%, Rat: 93%, Sheep: 77%

Characteristics: This is a rabbit polyclonal antibody against GHRHR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GHRHR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 337 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GHRHR

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Alternative Name: GHRHR

Background: GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dw
Alias Symbols: GHRFR, GHRHRpsv, GRFR, IGHD1B
Protein Interaction Partner: GHRH, GHRL, MLNR,
Protein Size: 337

Molecular Weight: 37 kDa

Gene ID: 2692

NCBI Accession: NM_001009824, NP_001009824

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process