LEFTY2 antibody (N-Term)

Catalog No. ABIN2777147

Product Details anti-LEFTY2 Antibody

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGPGAALTEE QLLGSLLRQL QLSEVPVLDR ADMEKLVIPA HVRAQYVVLL

Predicted Reactivity: Dog: 83%, Human: 100%, Pig: 77%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against LEFTY2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LEFTY2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LEFTY2

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Alternative Name: LEFTY2 (LEFTY2 Products)

Background: LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.
Alias Symbols: EBAF, LEFTA, LEFTYA, TGFB4
Protein Interaction Partner: ACSS3,
Protein Size: 366

Molecular Weight: 40 kDa

Gene ID: 7044

NCBI Accession: NM_003240, NP_003231

UniProt: O00292