UPP1 antibody (Middle Region)

Catalog No. ABIN2777157

The Rabbit Polyclonal anti-UPP1 antibody has been validated for WB. It is suitable to detect UPP1 in samples from Human, Mouse, Rat, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Dog and Rabbit.

Quick Overview for UPP1 antibody (Middle Region) (ABIN2777157)

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UPP1 Antibody

Binding Specificity: Middle Region

Sequence: ACGLQAAVVC VTLLNRLEGD QISSPRNVLS EYQQRPQRLV SYFIKKKLSK

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 77%, Rat: 85%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against UPP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UPP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 310 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UPP1

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Alternative Name: UPP1

Background: UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Alias Symbols: UDRPASE, UP, UPASE, UPP
Protein Interaction Partner: CTDP1, YRDC, WDR45B, WBP2, UCK2, UBE2D1, MPST, UBC, EBNA-LP, VIM,
Protein Size: 310

Molecular Weight: 34 kDa

Gene ID: 7378

NCBI Accession: NM_003364, NP_003355

UniProt: Q16831

Pathways: Ribonucleoside Biosynthetic Process