LMO2 antibody (N-Term)

Catalog No. ABIN2777181

The Rabbit Polyclonal anti-LMO2 antibody (ABIN2777181) specifically detects LMO2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Cow and Horse samples.

Quick Overview for LMO2 antibody (N-Term) (ABIN2777181)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LMO2 Antibody

Binding Specificity: N-Term

Sequence: RKSLDPSEEP VDEVLQIPPS LLTCGGCQQN IGDRYFLKAI DQYWHEDCLS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LMO2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: LMO2

Background: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: RBTN2, RBTNL1, RHOM2, TTG2
Protein Interaction Partner: ADAMTSL4, MBIP, HOOK1, TFPT, NOTCH2NL, KRTAP10-7, CCDC36, NUTM1, SPERT, FAM154A, CLHC1, KRT40, SSX2IP, CMTM5, MRFAP1L1, IFT43, C1orf94, LZTS2, TSC22D4, DBF4B, CCDC33, RINT1, NIF3L1, TRIM54, AGTRAP, ZFP64, BANP, STAT3, STAT1, SOX5, SKP1, ROCK1, REL, PRKG1,
Protein Size: 227

Molecular Weight: 24 kDa

Gene ID: 4005

NCBI Accession: NM_005574, NP_005565

Pathways: Chromatin Binding