TFCP2 antibody (N-Term)

Catalog No. ABIN2777203

The Rabbit Polyclonal anti-TFCP2 antibody has been validated for WB. It is suitable to detect TFCP2 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for TFCP2 antibody (N-Term) (ABIN2777203)

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFCP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TFCP2 Antibody

Binding Specificity: N-Term

Sequence: YSMSDVLALP IFKQEESSLP PDNENKILPF QYVLCAATSP AVKLHDETLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TFCP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFCP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 502 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFCP2

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Alternative Name: TFCP2

Background: TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Alias Symbols: CP2, LBP-1C, LSF, SEF, TFCP2C, LBP1C, LSF1D
Protein Interaction Partner: E2F8, NPEPL1, CDC73, MRPL11, KIAA1598, CBX8, TDRD1, CCDC94, ASAP3, C19orf73, FANCL, ZCCHC10, FAM64A, DNAJC27, TRAPPC12, POLL, TSPAN12, PLCB1, STMN2, MORF4L1, FARS2, EIF5B, PITPNM1, PPIG, GPANK1, BAG6, SUMO1, TCEA2, SDCBP, RBMS1, PSMD5, PPP3R2, PHF1, MRPL4
Protein Size: 502

Molecular Weight: 57 kDa

Gene ID: 7024

NCBI Accession: NM_005653, NP_005644

UniProt: Q12800