FOSL2 antibody (Middle Region)

Catalog No. ABIN2777246

This anti-FOSL2 antibody is a Rabbit Polyclonal antibody detecting FOSL2 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for FOSL2 antibody (Middle Region) (ABIN2777246)

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOSL2 Antibody

Binding Specificity: Middle Region

Sequence: PMRSGGGSVG AVVVKQEPLE EDSPSSSSAG LDKAQRSVIK PISIAGGFY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against FOSL2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOSL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FOSL2

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2, which encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: FRA2
Protein Interaction Partner: GMCL1, GOPC, LUZP4, CREB5, DNAJA3, TRAF1, FHL3, DDIT3, JUNB, UBC, SRA1, ATF1, EP300, SUMO2, JUND, JUN,
Protein Size: 326

Molecular Weight: 35 kDa

Gene ID: 2355

NCBI Accession: NM_005253, NP_005244

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism