MSX1 antibody (Middle Region)

Catalog No. ABIN2777275

This Rabbit Polyclonal antibody specifically detects MSX1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horseand has been mentioned in 1 publication.

Quick Overview for MSX1 antibody (Middle Region) (ABIN2777275)

Target: MSX1 (Msh Homeobox 1 (MSX1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MSX1 Antibody

Binding Specificity: Middle Region

Sequence: SLGAPDAPSS PRPLGHFSVG GLLKLPEDAL VKAESPEKPE RTPWMQSPRF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MSX1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MSX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MSX1 antibody (ABIN2777275)

Mizokami, Egashira, Takekoshi, Itoh, Itoh, Osamura, Matsumae: "Expression of MSX1 in human normal pituitaries and pituitary adenomas." in: Endocrine pathology, Vol. 19, Issue 1, pp. 54-61, (2009) (PubMed).

Target Details for MSX1

Target: MSX1 (Msh Homeobox 1 (MSX1))

Alternative Name: MSX1

Background: Slightly proximal to the Huntington disease locus, the human MSX1 gene is deleted in patients with Wolf-Hirschhorn syndrome. This gene is also called HOX7. The Msx family of vertebrate HOX genes was originally isolated by homology to the Drosophila msh (muscle segment homeo box) gene. This is a candidate gene for human cleft palate.
Alias Symbols: HOX7, HYD1, STHAG1
Protein Interaction Partner: MED19, NMNAT1, ING4, UBC, TLE2, PIAS1, PAX3, TLE4, LHX2, SUMO2, RGS7, SUMO1, TLE1, AES, CREBBP, TBP, TAF1, TP53, SP1, PAX9, POU2F1, MSX1, MSX2, HOXC8, DLX5, DLX2,
Protein Size: 297

Molecular Weight: 31 kDa

Gene ID: 4487

NCBI Accession: NM_002448, NP_002439

UniProt: P28360

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus