HOXB5 antibody (N-Term)

Catalog No. ABIN2777303

This anti-HOXB5 antibody is a Rabbit Polyclonal antibody detecting HOXB5 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for HOXB5 antibody (N-Term) (ABIN2777303)

Target: HOXB5 (Homeobox B5 (HOXB5))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HOXB5 Antibody

Binding Specificity: N-Term

Sequence: MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXB5 antibody (ABIN2777303)

Fu, Lui, Sham, Cheung, Tam: "HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 228, Issue 1, pp. 1-10, (2003) (PubMed).

Target Details for HOXB5

Target: HOXB5 (Homeobox B5 (HOXB5))

Alternative Name: HOXB5

Background: HOXB5 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
Protein Size: 269

Molecular Weight: 30 kDa

Gene ID: 3215

NCBI Accession: NM_002147, NP_002138

UniProt: P09067