CDX2 antibody (Middle Region)

Catalog No. ABIN2777319

This anti-CDX2 antibody is a Rabbit Polyclonal antibody detecting CDX2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for CDX2 antibody (Middle Region) (ABIN2777319)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDX2 Antibody

Binding Specificity: Middle Region

Sequence: QRRNLCEWMR KPAQQSLGSQ VKTRTKDKYR VVYTDHQRLE LEKEFHYSRY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CDX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CDX2 antibody (ABIN2777319)

Bell, Watson: "p38 MAPK regulates cavitation and tight junction function in the mouse blastocyst." in: PLoS ONE, Vol. 8, Issue 4, pp. e59528, (2013) (PubMed).

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background: CDX2 encodes a protein that plays an important role in gallbladder carcinogenesis with intestinal differentiation. Cdx2 is a highly sensitive marker for Barrett's esophagus.
Alias Symbols: CDX3, CDX-3
Protein Interaction Partner: CDK2, SMARCD1, SMARCB1, SMARCA4, SMARCA2, KDM5B, UBB, PAX6, GSK3B, EP300, CDX2, MAPK14, CREBBP, MAPK1, HNF1A, ACAT2,
Protein Size: 313

Molecular Weight: 34 kDa

Gene ID: 1045

NCBI Accession: NM_001265, NP_001256

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance