Advillin antibody (N-Term)

Catalog No. ABIN2777326

This anti-Advillin antibody is a Rabbit Polyclonal antibody detecting Advillin in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Advillin antibody (N-Term) (ABIN2777326)

Target: Advillin (AVIL)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Advillin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Advillin Antibody

Binding Specificity: N-Term

Sequence: SGERLXXXXX XKAMLLAKDI RDREGGGRAE IGVIEGDKEA ASPELMTVLQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Avil. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 829 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Advillin

Target: Advillin (AVIL)

Alternative Name: Avil

Background: Avil is a Ca2+-regulated actin-binding protein. It may have a unique function in the morphogenesis of neuronal cells which form ganglia. It is required for SREC1-mediated regulation of neurite-like outgrowth. It plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. It is involved in the formation of long fine actin-containing filopodia-like structures in fibroblast and is required for SREC1-mediated regulation of neurite-like outgrowth. Avil plays a role in ciliogenesis.
Alias Symbols: -
Protein Size: 829

Molecular Weight: 91 kDa

Gene ID: 79253

NCBI Accession: NM_024401, NP_077377

UniProt: Q9WU06

Pathways: Regulation of Actin Filament Polymerization