TBR1 antibody (Middle Region)

Catalog No. ABIN2777327

This anti-TBR1 antibody is a Rabbit Polyclonal antibody detecting TBR1 in WB. Suitable for Human, Mouse, Cow, Dog and Pig.

Quick Overview for TBR1 antibody (Middle Region) (ABIN2777327)

Target: TBR1 (T-Box Brain Gene 1 (TBR1))

Reactivity: Human, Mouse, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBR1 Antibody

Binding Specificity: Middle Region

Sequence: MAGANPYLGE EAEGLAAERS PLPPGAAEDA KPKDLSDSSW IETPSSIKSI

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 86%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against TBR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 682 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBR1

Target: TBR1 (T-Box Brain Gene 1 (TBR1))

Alternative Name: TBR1

Background: This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
Alias Symbols: MGC141978, TES-56, TBR-1
Protein Interaction Partner: UBC, CASK, TSPYL2,
Protein Size: 682

Molecular Weight: 74 kDa

Gene ID: 10716

NCBI Accession: NM_006593, NP_006584

UniProt: Q16650